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Only few studies have investigated the effects of GOS medium-term ingestion on the small intestinal epithelium characteristics. Sucrase activity was significantly increased in the intestinal mucosa recovered from animals fed the GOS diet without any detectable modification of lactase and phosphatase activities. Hyperproteic diet modifies microbiota composition and associated metabolites in rats. For full functionality of ResearchGate it is necessary to enable JavaScript. Millimolar concentrations of ammonia dose-dependently inhibit SCFA oxidation [37] and basal oxygen consumption in colonocytes [38]. European Journal of Nutrition 1. Mice received the experimental diets for 4 weeks and then the small intestine was collected to measure sucrase, lactase and alkaline phosphatase activities, to study the villus heights in the jejunum mucosa and to determine mucosal mucin content as well as MUC-2 and MUC-4 mRNAs expression by qRT-PCR.
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